AG Translationale Psychiatrie
- Arbeitsgruppenleiter:in:
Prof. Dr. Marianne Müller
- Forschungsschwerpunkte:
Tierexperimentelle Modelle für Stress und Resilienz
Identifikation der molekularen Mechanismen für Therapieansprechen bei Depression
Systembiologische Mechanismen psychischer Störungen
- Fünf wichtigste Publikationen:
Kalisch R, Russo SJ, Müller MB (2024). Neurobiology and systems biology of stress resilience. Physiol Rev 104(3):1205-1263. doi: 10.1152/physrev.00042.2023.
Ayash S, Lingner T, Ramisch A, Ryu S, Kalisch R, Schmitt U, Müller MB (2023). Fear circuit-based neurobehavioral signatures mirror resilience to chronic social stress in mouse. Proc Natl Acad Sci USA. 120 (17) e2205576120; doi: /10.1073/pnas.2205576120 (open access).
Lyons DM, Ayash S, Schatzberg AF, Müller MB (2023). Ecological validity of social defeat stressors in mouse models of vulnerability and resilience. Neurosci Biobehav Rev 145:105032. doi: 10.1016/j.neubiorev.2023.105032.
Van der Kooij M, Jene T, Miederer I, Hasch A, Voelxen N, Walenta S, Müller MB (2018). Chronic social stress-induced hyperglycemia in mice couples individual stress susceptibility to impaired spatial memory. Proc Natl Acad Sci USA. 115 (43) E10187-E10196. doi: 10.1073/pnas.1804412115 (open access).
Carrillo-Roa T, Labermaier C, Weber P, Herzog DP, Lareau C, Santarelli S, Wagner KV, Rex-Haffner M, Harbich D, Scharf SH, Nemeroff CB, Dunlop BW, Craighead WE, Mayberg HS, Schmidt MV, Uhr M, Holsboer F, Sillaber I, Binder EB, Müller MB (2017). Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity. PLoS Biol. 2017 15(12): e2002690.https://doi.org/10.1371/journal. pbio.2002690 (open access).
