AG Neuroprotektion Klinik für Anästhesiologie, UMM, FTN Mainz, ZFI Mainz
- Arbeitsgruppenleiter:in: Prof. Dr. Michael Schäfer
- Forschungsschwerpunkte:
Mausmodelle für akute Neurodegeneration, Hirnanatomie, Verhalten, Neuroinflammation, Zellkulturmodelle, Mikroglia, Astrocyten, …
- Fünf wichtigste Publikationen:
Depletion of regulatory T cells increases T cell brain infiltration, reactive astrogliosis, and interferon-γ gene expression in acute experimental traumatic brain injury. Krämer T, … Schäfer MKE. J Neuroinflammation. 2019 Aug 5;16(1):163. doi: 10.1186/s12974-019-1550-0. Erratum in: J Neuroinflammation. 2019 Sep 7;16(1):176. PMID:31383034.
Neuronal Growth and Behavioral Alterations in Mice Deficient for the Psychiatric Disease-Associated Negr1 Gene. Singh K, … Schäfer MKE. Front Mol Neurosci. 2018 Feb 9;11:30. doi: 10.3389/fnmol.2018.00030. eCollection 2018. PMID: 29479305.
Traumatic brain injury causes long-term behavioral changes related to region-specific increases of cerebral blood flow. Pöttker B, … Schäfer MKE. Brain Struct Funct. 2017 Dec;222(9):4005-4021. doi: 10.1007/s00429-017-1452-9. Epub 2017 Jun 6. PMID:28589257.
Down-regulation of neuronal L1 cell adhesion molecule expression alleviates inflammatory neuronal injury. Menzel L, … Zipp F, Schäfer MK. Acta Neuropathol. 2016 Nov;132(5):703-720. Epub 2016 Aug 20. PMID:27544757.
Lack of NG2 exacerbates neurological outcome and modulates glial responses after traumatic brain injury. Huang C, …, Schäfer MK. Glia. 2016 Apr;64(4):507-23. doi: 10.1002/glia.22944. Epub 2015 Dec 6. PMID:26638112.