International Medical Services
AG Waisman
- Arbeitsgruppenleiter:in: Prof. Dr. Ari Waisman
- Forschungsschwerpunkte:
- autoimmunity
- cytokines
- immune-tissue interactions
- Fünf wichtigste Publikationen:
Grigg JB, Shanmugavadivu A, Regen T, Parkhurst CN, Ahmed A, Joseph AM, Mazzucco M, Gronke K, Diefenbach A, Eberl G, Vartanian T, Waisman A*, Sonnenberg GF*. Antigen-presenting innate lymphoid cells orchestrate neuroinflammation. Nature 2021, 600(7890):707-712. *Equal contribution; DOI: 10.1038/s41586-021-04136-4
Regen T, Isaac S, De Oliveira Amorim A, Gonzalo Núñez N, Hauptmann J, Shanmugavadivu A, Klein M, Sankowski R, Mufazalov IA, Yogev N, Huppert J, Wanke F, Witting M, Grill A, Galvez EJC, Nikolaev A, Blanfeld M, Prinz I, Schmitt-Kopplin P, Strowig T, Reinhardt C, Prinz M, Bopp T, Becher B, Ubeda C, Waisman A. IL-17 controls the central nervous system autoimmunity through the intestinal microbiome. Science Immunology 2021, 6(56):eaaz6563; DOI: 10.1126/sciimmunol.aaz6563.
Hauptmann J, Johann L, Marini F, Kitic M, Colombo E, Mufazalov IA, Krueger M, Karram K, Moos S, Wanke F, Kurschus FC, Klein M, Cardoso S, Strauß J, Bolisetty S, Lühder F, Schwaninger M, Binder H, Bechman I, Bopp T, Agarwal A, Soares MP, Regen T, Waisman A. Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood-brain barrier. Acta Neuropathol 2020, 140(4):549-567; DOI: 10.1007/s00401-020-02187-x.
Bruttger J, Karram K, Wörtge S, Regen T, Marini F, Hoppmann N, Klein M, Blank T, Yona S, Wolf Y, Mack M, Pinteaux E, Müller W, Zipp F, Binder H, Bopp T, Prinz M, Jung S, Waisman A. Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System. Immunity 2015, 43(1):92-106; DOI: 10.1016/j.immuni.2015.06.012.
Yogev N, Frommer F, Lukas D, Kautz-Neu K, Karram K, Ielo D, von Stebut E, Probst HC, van den Broek M, Riethmacher D, Birnberg T, Blank T, Reizis B, Korn T, Wiendl H, Jung S, Prinz M, Kurschus FC, Waisman A. Dendritic cells ameliorate autoimmunity in the CNS by controlling the homeostasis of PD-1 receptor(+) regulatory T cells. Immunity 2012, 37(2):264-275; DOI: 10.1016/j.immuni.2012.05.025.
- Ansprechpartner:in:
Susanne Gahr
E-Mail: gahr@uni-mainz.de
